Retinoic Acid CAS: 302- 79-4 Retinoic Acid/All-Trans Retinoic Acid

DescriptionRetinoic acid is a metabolite of vitamin A (retinol) that mediates the functions of vitamin A required for growth and development. Retinoic acid is required in chordate animals, which includes all higher animals from fish to humans. During early embryonic development, retinoic acid generated in a specific region of th

Featured Products

Description

Retinoic acid is a metabolite of vitamin A (retinol) that mediates the functions of vitamin A required for growth and development. Retinoic acid is required in chordate animals, which includes all higher animals from fish to humans. During early embryonic development, retinoic acid generated in a specific region of the embryo helps determine position along the embryonic anterior/posterior axis by serving as an intercellular signaling molecule that guides development of the posterior portion of the embryo. It acts through Hox genes, which ultimately control anterior/posterior patterning in early developmental stages.
The key role of retinoic acid in embryonic development mediates the high teratogenicity of retinoid pharmaceuticals, such as isotretinoin used for treatment of cancer and acne. Oral megadoses of pre-formed vitamin A (retinyl palmitate), and retinoic acid itself, also have teratogenic potential by this same mechanism.

Basic Info

Chemical Nameall-trans-retinoic acid
Synonyms

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;retin-a;ATRA;13-cis-retinoic acid;aknoten;Expand

CAS No.302-79-4
Molecular FormulaC20H28O2
Molecular Weight300.43500
PSA37.30000
LogP5.60260

Safety Info

Safety StatementsS36/37-S45
HS Code2916209090
Risk StatementsR22; R38; R63
Hazard CodesXn
Caution StatementP301 + P312 + P330
Signal WordWarning
SymbolGHS07
Hazard DeclarationH302

Vitamin a Acid CAS: 302-79-4 Tretinoin/All-Trans-Retinoic Acid
Vitamin a Acid CAS: 302-79-4 Tretinoin/All-Trans-Retinoic Acid
Vitamin a Acid CAS: 302-79-4 Tretinoin/All-Trans-Retinoic Acid
Vitamin a Acid CAS: 302-79-4 Tretinoin/All-Trans-Retinoic Acid
Vitamin a Acid CAS: 302-79-4 Tretinoin/All-Trans-Retinoic Acid
Vitamin a Acid CAS: 302-79-4 Tretinoin/All-Trans-Retinoic Acid
Vitamin a Acid CAS: 302-79-4 Tretinoin/All-Trans-Retinoic Acid
Vitamin a Acid CAS: 302-79-4 Tretinoin/All-Trans-Retinoic Acid

Contact us

Please feel free to give your inquiry in the form below We will reply you in 24 hours